GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs11185790 | 1 | rs10881610 | chr10:91374833 | FLJ37201 | chr10:91451057-91457685:- | -0.17 | -3.76 | 0.000178 | Metabolic traits |
| BRCA | cis | rs56322409 | 1 | rs10882644 | chr10:97388579 | ENTPD1 | chr10:97471536-97637022:+ | 0.17 | 5.81 | 8.05E-9 | Blood metabolite levels |
| BRCA | cis | rs11190604 | 1 | rs10883492 | chr10:102206089 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.38 | 4.08E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883493 | chr10:102208188 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.32 | 7.37E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883496 | chr10:102221931 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.51 | 1.23E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883497 | chr10:102228519 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.48 | 1.6E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883499 | chr10:102232188 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.31 | 8.24E-24 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883500 | chr10:102238324 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.59 | 5.58E-25 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883501 | chr10:102238326 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.59 | 5.58E-25 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883502 | chr10:102238343 | SEC31B | chr10:102246403-102289636:- | -0.28 | -10.59 | 5.58E-25 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883503 | chr10:102275504 | SEC31B | chr10:102246403-102289636:- | -0.29 | -10.55 | 7.8E-25 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883504 | chr10:102280687 | SEC31B | chr10:102246403-102289636:- | -0.29 | -10.54 | 8.88E-25 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883505 | chr10:102280772 | SEC31B | chr10:102246403-102289636:- | -0.3 | -11.07 | 4.88E-27 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883506 | chr10:102289743 | SEC31B | chr10:102246403-102289636:- | -0.3 | -11.09 | 3.91E-27 | Palmitoleic acid (16:1n-7) plasma levels |
| BRCA | cis | rs11190604 | 1 | rs10883507 | chr10:102291275 | SEC31B | chr10:102246403-102289636:- | -0.3 | -11.09 | 3.91E-27 | Palmitoleic acid (16:1n-7) plasma levels |